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目的比较静滴利巴韦林+板蓝根冲剂口服与静滴利巴韦林治疗流行性腮腺炎的临床疗效。方法确诊的流行性腮腺炎病人88例,男性47例,女性41例;年龄4~12岁,平均(6.8±2.1)岁。随机分为治疗组45例,在一般补液、退热的同时加用利巴韦林注射液10~15 mg/(kg.d),静脉滴注1次/d,及板蓝根冲剂10 g,口服,3次/d;对照组43例,在一般补液、退热的同时加用利巴韦林10~15 mg/(kg.d),静脉滴注,1次/d,两组疗程均为7 d。结果两组发热、腮腺疼痛的消失、腮腺肿大的消退,治疗组分别为(3.0±0.6)d,(4.3±0.8)d,(5.2±0.7)d;对照组为(4.2±0.5)d,(4.8±0.9)d,(5.9±0.9)d,经t检验比较差异有统计学意义(P<0.01);临床有效率治疗组为95.56%,对照组为79.06%。经χ2检验差异有统计学意义(P<0.05)。结论利巴韦林+板蓝根治疗流行性腮腺炎较单纯使用利巴韦林疗效更好。
Objective To compare the clinical effects of intravenous infusion of ribavirin + Banlangen granules and intravenous infusion of ribavirin in the treatment of mumps. Methods: Eighty-eight mumps patients were diagnosed, including 47 males and 41 females, aged 4 to 12 years (mean, 6.8 ± 2.1) years. Randomly divided into treatment group, 45 cases of general rehydration, antipyretic plus ribavirin injection 10 ~ 15 mg / (kg.d), intravenous infusion 1 / d, and Ban Langen granules 10 g, orally , 3 times / d; control group of 43 cases, the general rehydration, antipyretics plus ribavirin 10 ~ 15 mg / (kg.d), intravenous drip, 1 / d, the two groups were 7 d. Results The fever of the two groups, the disappearance of parotid pain and the regression of parotid gland enlargement were (3.0 ± 0.6) days and (4.3 ± 0.8 days) in the treatment group (5.2 ± 0.7 days) and (4.2 ± 0.5 days) in the control group , (4.8 ± 0.9) d and (5.9 ± 0.9) d, respectively. The difference was statistically significant by t test (P <0.01). The clinical effective rate was 95.56% in the treatment group and 79.06% in the control group. The χ2 test showed significant difference (P <0.05). Conclusion Ribavirin + Radix isatidis is more effective than ribavirin alone in the treatment of mumps.