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目的了解不同病原体脑膜炎特征性的脑脊液变化规律和头颅ＣＴ表现，为病因诊断及治疗提供依据。方法经腰椎穿刺或颈椎侧方穿刺进行脑脊液常规、生化及免疫球蛋白检查，并进行头颅ＣＴ扫描。结果１５１例不同病原体脑膜炎分别由病毒、化脓菌、结核杆菌、新型隐球菌引起，依病原体不同，脑脊液改变显示出一定的规律性；ＣＴ扫描能显示病变部位、范围及程度，不同病原体脑膜炎亦有一定的特征性改变。结论脑膜炎患者的脑脊液常规、生化及免疫球蛋白检查可为病因诊断提供重要依据，头颅ＣＴ扫描对诊断、治疗、判断预后均有较大的参考价值
Objective To understand the regularity of cerebrospinal fluid (CSF) changes and cranial CT features of different pathogens meningitis, and to provide evidence for the diagnosis and treatment of etiology. Methods Conventional, biochemical and immunoglobulin tests were performed on the cerebrospinal fluid (CSF) through lumbar puncture or lateral cervical puncture, and CT scans were performed. Results 151 cases of meningitis caused by different pathogens were caused by viruses, pyogenic bacteria, Mycobacterium tuberculosis and Cryptococcus neoformans respectively. Cerebrospinal fluid changes showed some regularity according to different pathogens. CT scan showed the location, extent and degree of lesions, meningitis of different pathogens There are also some characteristic changes. Conclusion Conventional, biochemical and immunoglobulin tests of cerebrospinal fluid in patients with meningitis may provide an important basis for the diagnosis of etiology. The CT scan of head has a great reference value for diagnosis, treatment and prognosis