论文部分内容阅读
目的:提高对膀胱前列腺共存肿瘤的诊断与治疗水平。方法:结合文献回顾性分析14例膀胱前列腺共存肿瘤患者的临床和病理资料。结果:以膀胱肿瘤首诊11例,术前均经膀胱镜活检病理证实为膀胱移行细胞癌(9例)、鳞癌(2例),该组有3例行经直肠前列腺穿刺活检,结果2例为前列腺癌,1例为前列腺增生症,该例与余8例行膀胱前列腺切除或TURBT+TURP后病理证实为前列腺癌。术后随访6～37个月。1例术后23个月死于心梗;1例术后10个月死于全身广泛转移和并发症;1例失访;8例无瘤生存。以前列腺肿瘤首诊3例分别行膀胱部分切除术+双睾丸切除术、前列腺癌根治术+TURBT、姑息性输尿管皮肤造瘘术,随访42、16、25个月,2例术后死于多发性转移,1例无瘤生存。结论:膀胱前列腺共存肿瘤是较少见的一种多原发肿瘤,临床上易漏诊。直肠指检、经直肠B超、PSA测定、活检和膀胱镜检的综合应用是目前诊断膀胱前列腺共存肿瘤的主要方法。两者共存并不提示预后不良。
Objective: To improve the diagnosis and treatment of bladder prostatic coexisting tumors. Methods: The clinical and pathological data of 14 patients with cystadenocarcinoma coexisting tumor were retrospectively analyzed. Results: The first diagnosis of bladder cancer in 11 cases were confirmed by cystoscopy biopsy before surgery for bladder transitional cell carcinoma (9 cases), squamous cell carcinoma (2 cases), the group of 3 cases of transrectal prostate biopsy, the results of 2 One case of prostate cancer, one case of benign prostatic hyperplasia, the case and the remaining 8 cases of bladder resection or TURBT TURP pathologically confirmed as prostate cancer. Postoperative follow-up 6 to 37 months. One patient died of myocardial infarction at 23 months after operation. One patient died of extensive systemic metastases and complications at 10 months after operation. One patient lost follow-up and eight patients had no tumor-free survival. The first diagnosis of prostate cancer were 3 cases of partial partial resection of the bladder + double orchiectomy, radical prostatectomy + TURBT, palliative ureterocostomy, followed up for 42, 16 and 25 months, 2 died of multiple postoperative complications Sexual transfer, 1 case of tumor-free survival. Conclusions: Bladder prostate coexisting tumor is a rare multi-primary tumor, which is easily missed by clinic. The combined use of digital rectal examination, transrectal B-ultrasound, PSA measurement, biopsy and cystoscopy is currently the primary method for the diagnosis of bladder prostatic co-existing tumors. Co-existence between the two does not suggest a poor prognosis.