Hypoxia promotes cell proliferation by modulating E2F1 in chicken pulmonary arterial smooth muscle c

• 作 者: Ying Yang Feng Sun Chen Zhang
• 机 构: StateKeyLaboratoryofAnimalNutrition,DepartmentofAnimalNutritionandFeedScience,DepartmentofPharmacy,D
• 出 处: 畜牧与生物技术杂志：英文版
• 发表日期: 2013年3期
• 关键词: 肺动脉平滑肌细胞 细胞增殖 细胞调控 缺氧 DNA合成 siRNA 鸡 蛋白质水平 E2F1 Hypoxia Proliferation Pulmonar
• 基金项目: Acknowledgements This work was supported by the Yangtze River Scholar and Innovation Research Team Development Program （Project No. IRT0945）, and grants from the National Natural Science Foundation of

In this study,we sought to investigate the expression of the transcription factor E2F1 in chicken pulmonary arterial smooth muscle cells upon hypoxia exposure,as well as the role that E2F1 played in the regulation of cell proliferation.Isolated chicken pu