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目的：探索盐酸二氢埃托啡对足月单胎初产妇分娩的镇痛效果。方法：选用１９９４年８月至９月间初产妇４０例为用药组，另选用同期同样条件４０例初产妇不给药为对照组。２组产妇年龄２３．０±ｓ１．０ａ（２１～２７ａ），孕周３８．０±１．４ｗｋ（３７～４１ｗｋ）用药组产妇宫口开大３ｃｍ后，舌下含盐酸二氢埃托啡２０μｇ，若３０ｍｉｎ后无镇痛作用，再加２０μｇ，总量在４０μｇ内。结果：用药组镇痛总有效率达９２％，与对照组比Ｐ＜０．０１。分娩第１产程被缩短（Ｐ＜０．０１），２组的分娩方式，产后出血量及新生儿Ａｐｇａｒ评分无明显差别。结论：二氢埃托啡用于分娩镇痛效果好，显效快，使用简便，未见明显不良反应。与对照组比镇痛效果非常明显。
Objective: To explore the analgesic effect of dihydroetorphine hydrochloride on full-term singleton primipara. Methods: 40 cases of primipara between August and September of 1994 were selected as the medication group, and 40 cases of primipara of the same condition were chosen as the control group. Two groups of maternal age 23.0 ± s1.0a (21 ~ 27a), gestational age 38.0 ± 1.4wk (37 ~ 41wk) medication group maternal cervix open 3cm, the sublingual hydrochloric dihydrotestination 20μg, if no analgesic effect after 30min, plus 20μg, the total within 40μg. Results: The total effective rate of analgesic in the medication group was 92%, which was significantly lower than that in the control group (P <0.01). The first stage of labor was shortened (P <0.01). There was no significant difference in the mode of delivery, the amount of postpartum hemorrhage and Apgar score in the two groups. Conclusion: Dihydroetorphine is effective in analgesia during labor and has obvious effect fast, easy to use and no obvious adverse reaction. Compared with the control group analgesic effect is very obvious.