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目的:评价对急性下呼吸道细菌感染患者采用左氧氟沙星序贯疗法治疗的临床疗效、安全性。方法:对本院2015年7月-2016年7月收治的100例急性下呼吸道细菌感染患者进行观察,采用随机分组法分为研究组与参照组,参照组采用头孢呋辛治疗,研究组采用左氧氟沙星序贯疗法治疗。治疗10-15d,观察两组治疗效果。结果:研究组总有效率明显高于参照组(P<0.05);研究组不良反应明显比参照组低有统计学意义P<0.05。结论:左氧氟沙星序贯疗法对病原菌的清除率高,不良反应低,对急性下呼吸道细菌感染的疗效安全可靠,值得推广。
Objective: To evaluate the clinical efficacy and safety of sequential levofloxacin therapy for patients with acute lower respiratory tract bacterial infections. Methods: A total of 100 patients with acute lower respiratory tract bacterial infections admitted to our hospital from July 2015 to July 2016 were observed. The patients were divided into study group and reference group randomly. The reference group was treated with cefuroxime. The study group adopted Levofloxacin sequential therapy. The treatment of 10-15d, observe the effect of two groups. Results: The total effective rate of the study group was significantly higher than that of the reference group (P <0.05). The adverse reaction rate of the study group was significantly lower than that of the reference group (P <0.05). Conclusion: The sequential therapy of levofloxacin has high clearance rate of pathogenic bacteria and low adverse reactions, which is safe and reliable for the treatment of acute lower respiratory tract bacterial infections and is worth promoting.