论文部分内容阅读
目的 :研究以紫杉醇为主联合化疗治疗晚期乳腺癌的临床疗效及毒副反应。方法 :应用紫杉醇与表阿霉素联合化疗治疗 3 1例晚期乳腺癌 ,观察其疗效及毒副反应情况。结果 :3 1例晚期乳腺癌总有效率 5 4 8% ,其中初治组有效率 63 6% ,复治组有效率 5 0 %。其毒副作用为 :骨髓抑制 ,脱发 ,关节肌肉酸痛 ,神经毒性及面色潮红 ,胃肠道反应轻微。结论 :以紫杉醇为主联合化疗治疗晚期乳腺癌疗效肯定 ,毒性反应经对症处理后可以耐受
Objective: To study the clinical efficacy and side effects of paclitaxel-based combination chemotherapy in the treatment of advanced breast cancer. Methods: 31 cases of advanced breast cancer were treated with paclitaxel and epirubicin in combination with chemotherapy. The curative effect and toxicity were observed. Results: The total effective rate of 51 cases of advanced breast cancer was 54.8%, of which 63.6% in initial treatment group and 50% in retreatment group. The toxic side effects: myelosuppression, hair loss, joint muscle soreness, neurotoxicity and flushing, mild gastrointestinal reactions. Conclusion: Paclitaxel-based chemotherapy in the treatment of advanced breast cancer is positive, and the toxicity can be tolerated after symptomatic treatment