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关于在伴有出血倾向特别是在白血病时血小板中5-羟色胺含量的资料不多,且结果不一。这可能是由于测定方法不同和未考虑血小板数的变动之故。检查了50名患者,其中21例慢淋、18例骨髓增殖综合征(慢粒、骨髓纤维化、红细胞增多症)、11例急性白血病。13例有出血倾向,7例血小板明显减少(低于10万),5例增多(高于50万)。急性白血病血小板中5-羟色胺降低最为显著,仅
There is not much information on the serotonin content in platelets associated with bleeding tendency, especially in leukemia, and the results are mixed. This may be due to different measurement methods and does not take into account changes in platelet count. A total of 50 patients were examined, including 21 cases of chronic lymphocytic leukemia, 18 cases of myeloproliferation syndrome (CML, myelofibrosis, polycythemia) and 11 cases of acute leukemia. Thirteen had a tendency to bleed, seven significantly reduced platelets (less than 100,000), and five more (more than 500,000). The most significant reduction in serotonin in acute leukemia platelets, only