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用ELISA法对159例孕产妇及新生儿血分别检测HBsAg,HbeAg进行HBV宫内传播率的分析及影响因素的病例对照研究。结果显示:新生儿出生时HBsAg阳性者16例,HBV宫内传播率994%(16/159),HBsAg、HBeAg双阳性母亲宫内传播率1739%(16/69)。多元logistic回归分析将母血HBeAg阳性、性别、产后出血、产程及羊水污染选入模型(剔除P值为010),OR值(OR95%可信区间)分别为843(204—3476)、486(133—1738)、143(103—196)、112(100—125)及014(002—105)。
159 cases of pregnant women and newborns by ELISA were detected HBsAg, HBeAg intrauterine infection rate of analysis and case-control study of influencing factors. The results showed that 16 cases were HBsAg positive and 994% (16/159) intrauterine HBV intrauterine infection. The intrauterine transmission rate of HBsAg and HBeAg double positive mothers was 1739% (16/69). Multivariate logistic regression analysis included maternal blood HBeAg positive, gender, postpartum haemorrhage, labor and amniotic fluid contamination in the model (excluding P value 010), OR (OR 95% confidence interval) were 843 (204 -34.76), 486 (133-1738), 143 (103-196), 112 (100-125) and 014 (0) 02-1 05).