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肾病是糖尿病最可怕的并发症之一，然而对非胰岛素依赖型糖尿病（NIDDM）肾病进展的危险因素只有少数研究。已有提示不仅血糖调控失常而且肾血流动力学改变，如肾小球内高压在糖尿病肾病的发展中也起着重要作用。许多动物模型显示局灶节段性肾小球硬化和动脉粥样硬化似具有共同
Kidney disease is one of the most horrendous complications of diabetes, yet there are only a few studies on the risk factors for the progression of non-insulin-dependent diabetes mellitus (NIDDM) nephropathy. It has been suggested that not only dysregulation of blood glucose and changes in renal hemodynamics, such as glomerular hypertension also play an important role in the development of diabetic nephropathy. Many animal models have shown that focal segmental glomerulosclerosis and atherosclerosis seem to be common