Interleukin-10 modified dendritic cells induce allo-hyporesponsiveness and prolong small intestine a

• 作 者: MinZhu Ming-FaWei FangLiu Hui-
• 机 构: DepartmentofPediatricSurgery,DepartmentofBums
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2003年11期
• 关键词: 白细胞介素-10 树突状细胞 小肠移植 同种异体移植 排斥反应

AIM: To investigate whether TL-10-transduced dendritic cells (DCs) could induce tolerogenicity and prolong allograft survival in rat intestinal transplantation.METHODS: Spleen-derived DCs were prepared and genetically modified by hTL-10 gene. The level of