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目的:探讨氨溴索气管内灌洗加肺表面活性物质在新生儿胎粪吸入综合征治疗中的价值。方法:在选取本院2014年9月至2015年9月诊治的胎粪吸入综合征新生儿72例作研究对象,将本组新生儿依据随机抽样法分为观察组(n=36)和对照组(n=36),观察组以常规综合治疗为基础,同时采取氨溴索气管内灌洗加肺表面活性物质治疗,对照组则在常规治疗基础上应用氨溴索气管内灌洗治疗,比较两组患儿的治疗效果、并发症发生率以及机械通气时间、住院时间。结果:两组患儿的并发症发生率、治疗总有效率、机械通气时间和住院时间比较,差异具有统计学意义(P<0.05)。结论:氨溴索气管内灌洗加肺表面活性物质在新生儿胎粪吸入综合征治疗中的价值显著,可明显降低患儿的并发症发生率,缩短其机械通气时间,促使其早日康复出院。
Objective: To investigate the value of ambroxol tracheal lavage plus pulmonary surfactant in the treatment of neonatal meconium aspiration syndrome. Methods: Seventy-two neonates with meconium aspiration syndrome diagnosed and treated in our hospital from September 2014 to September 2015 were selected as study subjects. The neonates were divided into observation group (n = 36) and control group according to random sampling method (N = 36). The observation group was based on the conventional comprehensive treatment. At the same time, ambroxol tracheal lavage plus pulmonary surfactant was used. In the control group, ambroxol tracheal lavage was used on the basis of routine treatment. The treatment effect, complication rate, mechanical ventilation time and hospital stay of the two groups were compared. Results: The incidence of complications, the total effective rate of treatment, the duration of mechanical ventilation and hospital stay in both groups were significantly different (P <0.05). Conclusion: Ambroxol tracheal intubation plus pulmonary surfactant has a significant value in the treatment of neonatal meconium aspiration syndrome, which can significantly reduce the incidence of complications and shorten the duration of mechanical ventilation and promote its early discharge and recovery .