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本文对１９８５～１９８７、１９８８～１９９０年华山医院临床分离的肺炎杆菌进行抗菌药药敏测定及耐药性分析。肺炎杆菌已成为临床分离的革兰氏阳性杆菌常见菌之一，各阶段该菌分别居第２、３和４位。几乎全部菌株均对氨苄西林耐药，但大多对头孢呋新、头孢噻肟、头孢他定和阿米卡星敏感。院内菌株比院外菌株耐药。根据肺炎杆菌对各种氨基糖苷类的敏感性，将测试菌分成产ＡＡＣ（３）－Ⅱ（３１．９％）、产ＡＡＣ（３）－Ⅱ和ＡＡＣ（６′）－Ⅰ（７．７％）和不产ＡＡＣ钝化酶三类。根据药敏测定结果，讨论了肺炎杆菌院内或院外菌株所致感染选用抗菌药的方案。
In this paper, the clinical isolates of Klebsiella pneumoniae from 1985 to 1987, 1988 to 1990 were tested for antimicrobial susceptibility and drug resistance. Klebsiella pneumoniae has become one of the most common Gram-positive bacilli in clinical isolates. Almost all strains were resistant to ampicillin, but most were sensitive to ceftiofur, cefotaxime, ceftazidime and amikacin. Hospital strains resistant strains than outside the hospital. According to the sensitivity of Klebsiella pneumoniae to various aminoglycosides, the tested bacteria were divided into AAC (3) -II (31.9%), AAC (3) -II and AAC (6 ’) - Ⅰ %) And does not produce AAC inactivation enzyme three categories. According to the results of the drug sensitivity test, the antibacterial drugs were selected for the infection of Klebsiella pneumoniae in hospital or out of hospital.