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目的探讨综合治疗小儿手足口病的临床疗效。方法将我院收治的小儿手足口病126例,随机分为治疗组和对照组,治疗组采用病毒唑、西咪替丁、喜炎平及山香圆颗粒综合治疗,对照组采用病毒唑治疗,观察两组患者的临床疗效及其症状、体征、发热改善时间及并发症发生情况。结果治疗组总有效率为97.1%,对照组总有效率为69.0%,治疗组较对照组差异有统计学意义(P<0.05)。同时,治疗组退热,口腔疱疹消退及手足臀部皮疹消退时间显著优于对照组,具有统计学意义(P<0.05)。结论病毒唑、西咪替丁、喜炎平及山香圆颗粒临床综合治疗小儿手足口病具有较好的疗效,且能明显缩短病程,值得临床推广应用。
Objective To investigate the clinical effect of comprehensive treatment of hand-foot-mouth disease in children. Methods 126 cases of HFMD in our hospital were randomly divided into treatment group and control group. The treatment group was treated with ribavirin, cimetidine, Xiyanping and Shanxiangyuan granules. The control group was treated with Ribavirin, The clinical efficacy, symptoms, signs, time to improvement of fever and complication of the two groups were observed. Results The total effective rate was 97.1% in the treatment group and 69.0% in the control group. The difference between the treatment group and the control group was statistically significant (P <0.05). At the same time, the treatment group fever, oral herpes regression and hand, foot and hip rash subsided significantly better than the control group, with statistical significance (P <0.05). Conclusion Ribavirin, cimetidine, Xiyanping and Shanxiangyuan clinical treatment of children with hand-foot-mouth disease has a good curative effect, and can significantly shorten the course of disease, is worthy of clinical promotion and application.