Protective effect of bicyclol against bile duct ligation-inducedhepatic fibrosis in rats

• 作 者: Zhen Yong-Zhan Li Na-Ren He
• 机 构: HebeiUnitedUniv,ChineseAcadMedSci,PekingUnionMedColl
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2015年23期
• 关键词: BICYCLOL Rat BILE DUCT LIGATION Liver FIBROSIS Gene expression profile BicyclolR
• 基金项目: Supported by the National Natural Science Foundation of China,No.81170409,No.81201281,the National S&T, Major Special Project on Major New Drug Innovation,No.2012ZX09301002-001,the Wang Bao En Liv

AIM： to evaluate the protective effect of bicyclolagainst bile duct ligation （BDL）-induced hepatic fibrosisin rats.METHODS： Sprague-Dawley male rats underwentBDL and sham-operated animals were used as healthycontrols. The BDL rats were divided into two gr