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目的:探讨应用预扩张颈横动脉前穿支皮瓣整复大面积面颈部瘢痕并用对侧预扩张胸部随意皮瓣接力修复供区的临床效果。方法:采用回顾性队列研究方法。2008年5月—2018年12月，解放军总医院第四医学中心收治10例烧伤后大面积面颈部瘢痕患者，其中男8例、女2例，年龄10~55岁。Ⅰ期手术中，根据瘢痕大小将2个相同容量的皮肤软组织扩张器（额定容量为250~600 mL）分别置入胸部左、右侧后扩张皮肤，总生理盐水注入量为扩张器额定容量的2~4倍。Ⅱ期手术中，用一侧面积为12 cm×9 cm~24 cm×16 cm的预扩张颈横动脉前穿支皮瓣，修复瘢痕切除松解后形成的12 cm×8 cm~23 cm×15 cm的缺损；将对侧与前述穿支皮瓣同等面积的预扩张胸部随意皮瓣舒展，修复前述穿支皮瓣转移后形成的8 cm×6 cm~17 cm×14 cm的继发缺损。观察颈横动脉穿支探查情况、皮瓣转移与成活情况、损伤修复情况、并发症情况，随访观察供受区外观、相关功能以及患者满意度。结果:本组10例患者的颈横动脉穿支均稳定出现，全部皮瓣均无张力转移至受区并成活，面颈部损伤均成功修复，无常见并发症发生。随访6个月~8年，预扩张颈横动脉前穿支皮瓣颜色、质地与周围组织匹配，患者抬头、旋转颈部等功能较术前明显改善，第1供区移植皮瓣颜色、质地与原皮肤相匹配，手术切口遗留线性瘢痕，9例患者对供受区外观和功能恢复表示满意。结论:预扩张颈横动脉前穿支皮瓣颜色、质地与面颈部匹配良好，可修复面积大，切取该皮瓣后继发创面采用预扩张胸部随意皮瓣同期修复，胸部供区损伤减轻，该接力修复方法是大面积面颈部瘢痕整复的良好选择。“,”Objective:To explore the clinical effects of pre-expanded anterior perforator flap of transverse cervical artery in extensive facial and cervical scar reconstruction and contralateral pre-expanded thoracic random flap in relay in donor site repair.Methods:A retrospective cohort study was conducted. From May 2008 to December 2018, 10 patients with extensive facial and cervical scar after burns were treated in the Fourth Medical Center of PLA General Hospital, including 8 males and 2 females, aged 10-55 years. In the first stage of operation, two skin and soft tissue expanders of the same volume (with rated capacity of 250-600 mL) were respectively placed in the right side and left side of the chest according to the size of scar, and then the skin was expanded. The total amount of normal saline injected was 2 to 4 times of the rated capacity of the expander. In the second stage, the defect with area of 12 cm×8 cm-23 cm×15 cm caused by scar resection and release was repaired with unilateral pre-expanded anterior perforator flap of transverse cervical artery with area of 12 cm×9 cm-24 cm×16 cm. The contralateral pre-expanded thoracic random flap with the same area as that of the above-mentioned perforator flap was extended to repair the secondary defect with area of 8 cm×6 cm-17 cm×14 cm formed after transfer of the above-mentioned perforator flap. The exploration of perforating branch of transverse cervical artery, flap transfer and survival, injury repair, and complications were observed. The appearance and related function of donor and recipient sites and satisfaction of patients were followed up.Results:The perforating branches of transverse cervical artery appeared stably in the 10 patients. All the flaps were transferred to the recipient area without tension and survived. Both facial and cervical injuries were repaired successfully with no common complications. During the follow-up of 6 months-8 years, the color and texture of the pre-expanded anterior perforator flap of transverse cervical artery matched with the surrounding tissue, the functions of head raising and neck rotation of patients were significantly improved compared with those before operation, the color and texture of the flap transplanted in the first donor site matched with the original skin, linear scar left at the surgical incision, and 9 patients were satisfied with the restoration of the appearance and function of donor and recipient sites.Conclusions:The color and texture of the pre-expanded anterior perforator flap of transverse cervical artery match well with the face and neck, and the repairable area is large. After the perforator flap is removed, the secondary wound can be repaired with the pre-expanded thoracic random flap at the same time, and the injury of the chest donor site is alleviated. This relay repair method is a good choice for reconstructing extensive facial and cervical scar.