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色氨酸(tryptophan)为人体内不可缺少的一种氨基酸,不能在体内合成,靠摄取食物而得,可通过血流运送到脑,转化为血清素(sertonin)。动物实验证实,增加脑的血清素含量可止痛。因此根管治疗术前使用色氨酸有可能防止其术后可能发生的疼痛,且无副作用。本文目的旨在确定色氨酸是否有上述作用。作者选择患牙从未作过根管治疗的连续50例病人作试验,25例服用色氨酸,另25例服用剂量相同的安慰剂作对照。治疗开始前询问病人,估计疼痛强度。强度从0～10,0示无疼瘸,10示剧烈疼痛。然后立即给病人服药0.5g/4小时,连续服至试验完毕。试
Tryptophan is an indispensable amino acid in human body. It can not be synthesized in the body and can be derived from ingesting food. It can be transported to the brain through blood flow and converted into sertonin. Animal experiments confirmed that increased brain serotonin content can relieve pain. Therefore, the use of tryptophan before the root canal treatment may prevent its potential pain after surgery, and no side effects. The purpose of this article is to determine whether tryptophan has the above effects. The authors selected 50 consecutive patients who had never been underwent endodontic treatment of the affected tooth for testing, 25 taking tryptophan, and the other 25 taking the same dose of placebo as a control. Ask the patient before treatment begins to assess pain intensity. Intensity from 0 to 10,0 showed no pain lame, 10 showed severe pain. And then immediately give the patient medication 0.5g / 4 hours, continuous service until the test is completed. test