异体脱钙骨基质骨粒复合骨水泥骨缺损修复材料结构特征及生物力学性能

• 作 者: 周勇 范清宇 蔡和平
• 机 构: Department of Orthopaedics, Tangdu Hospital,Fourth Military Medical University, Xi’ an 710038, Shann
• 出 处: 中国临床康复
• 发表日期: 2003年4期
• 关键词: osteogenesis bone matrix bone morphogenetic proteins biocompatible materials mic

AIM: To analyze constructive and biomechanical properties of different quality ratio material impregnated decalcified bone matrix (DBM) with bone cement (BC) . METHODS: The DBM particles and the materials impregnated 0 rmg/g, 300 mg/g and 400 mg/g maas ratio DBM particles with BC were made according to the methods of Urist et al. The compound material constructions were observed by scanning electron microscope and the biomechanical properties were measured by Instron mechanics testing-machine. RESULTS: The DBM particles with irregular gaps existing within interspace were connected with BC by the multipoint mode in the compound material. The ultimate compressive strength were 0 mg/g DBM in (59.3 ±2.2) MPa, 300 mg/g in (27.1 ±1.8) MPa, 400 mg/g in (19.3±1.6) MPa. The ultimate bending strength were 0 mg/g in (54.3±3.7) MPa, 300 mg/g in (18.5±1.1) MPa, 400 mg/g in (13.3±1.4) MPa. CONCLUSION: The materials of DBM impregnated with BC had perfect plastic property with much more irregular gaps existing within interspace. The materials could provide abundant biomechanical support.