Novel D-galactosamine-induced cynomolgus monkey model of acute liver failure

• 作 者: Lei Feng Lei Cai Guo-Lin He Ju
• 机 构: DepartmentofHepatobiliarySurgeryII,StateKeyLaboratoryofOrganFailureResearch
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2017年42期
• 基金项目: Supported by The National Natural Science Foundation of China,No.81470875,The Natural Science Foundation of Guangdong Province,China,No.2014A030312013,The Science and Technology Planning Project of Gu

AIM To establish a simplified, reproducible D-galactosamineinduced cynomolgus monkey model of acute liver failure having an appropriate treatment window. METHODS Sixteen cynomolgus monkeys were randomly dividedinto four groups(A, B, C and D) after intracr