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目的:探讨口腔扁平苔藓(OLP)患者及其糜烂症状急性发作发生的流行病学特征和临床特点。方法:对上海交通大学医学院附属第九人民医院口腔黏膜科就诊并随访存档的OLP病例档案进行回顾性分析研究,筛选影响OLP糜烂症状急性发作的相关因素。结果:通过对出现OLP糜烂症状急性发作病例的临床特征多因素Logistic回归分析,筛选出对糜烂发作最具影响的危险因素依次为:刺激性饮食、饮酒、吸烟、高血糖、精神因素、年龄。结论:OLP患者中有刺激性饮食习惯、吸烟习惯、饮酒习惯、情绪波动、血糖升高以及60岁以上老年患者易出现糜烂症状急性发作。
Objective: To investigate the epidemiological characteristics and clinical features of patients with oral lichen planus (OLP) and their acute exacerbation of erosive symptoms. Methods: A retrospective analysis was conducted on the OLP case files of oral mucosal department and the follow-up archives of the Ninth People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine to screen out the relevant factors influencing the acute exacerbation of OLP. Results: By multivariate Logistic regression analysis of the clinical features of acute exacerbation of OLP, the most risk factors of erosion were screened out as irritating diet, alcohol consumption, smoking, hyperglycemia, mental factors and age. Conclusion: OLP patients have irritating eating habits, smoking habits, drinking habits, mood swings, elevated blood glucose and elderly patients over 60 years of age prone to acute exacerbation of erosion symptoms.