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目的:探讨重型颅脑损伤并发高渗性非酮症糖尿病昏迷的发病机制、临床特点及救治措施。方法:对2000-03/2008-10间收治的46例重型颅脑损伤并发高渗性非酮症糖尿病昏迷患者的临床资料作回顾性分析。结果:本组经确诊后予补液纠正脱水、应用胰岛素、补钾及防治并发症等综合治疗,死亡9例,重残植物生存9例,恢复良好28例。结论:重型颅脑损伤患者并发高渗性非酮症糖尿病昏迷,预后不佳,早期诊治有助于改善预后。
Objective: To investigate the pathogenesis, clinical features and treatment of severe craniocerebral injury complicated with hyperosmolar nonketotic diabetic coma. Methods: The clinical data of 46 cases of severe craniocerebral injury with hyperosmolar nonketotic diabetic coma admitted between 2000-03 and 2008-10 were analyzed retrospectively. Results: After the diagnosis of dehydration in this group to correct dehydration, the application of insulin, potassium and prevention of complications such as comprehensive treatment, 9 patients died, 9 patients with severe residual survival, recovery of 28 cases. Conclusion: Patients with severe craniocerebral injury complicated by hyperosmolar nonketotic diabetic coma have poor prognosis. Early diagnosis and treatment may help to improve prognosis.