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目的通过研究影响中央区淋巴结转移的因素,探讨PTMC的适宜术式。方法回顾性分析2012年4月—2013年3月期间接受手术治疗并行中央区淋巴结清扫的140例PTMC患者,统计年龄、性别、病理学特征、术前超声诊断结果等,探讨患者临床特点与中央区淋巴结转移的关系。结果年龄<45岁、癌灶多发、癌灶侵及甲状腺被膜、癌灶无包膜结构者转移率分别为41.8%、44.9%、77.8%、35.6%,PTMC中央区淋巴结转移与之相关(P<0.05)。结论年龄<45岁、癌灶多发、癌灶侵及甲状腺被膜、癌灶无包膜的PTMC患者应考虑行预防性中央区淋巴结清扫。
Objective To study the factors influencing the lymph node metastasis in central area and to explore the appropriate surgical procedure for PTMC. Methods The clinical data of 140 patients with PTMC who underwent surgical treatment of central lymph node dissection between April 2012 and March 2013 were retrospectively analyzed. The clinical features, such as age, sex, pathological features and preoperative ultrasonographic diagnosis, District lymph node metastasis. Results The metastatic rates of lymph node metastasis were 41.8%, 44.9%, 77.8%, 35.6% respectively in the central area of PTMC <0.05). CONCLUSIONS: Patients with PTMC less than 45 years old who have many cancers, invaded the thyroid gland, and have no capsule in the foci should consider prophylactic central lymph node dissection.