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目的 :探讨一日法口服乙酰唑胺 (ACZ)负荷脑血流显像早期诊断缺血性脑血管疾病的临床价值。方法 :对 17例缺血性脑血管病患者在一日内行静息显像和口服ACZ负荷显像 ,负荷前后测患者的血气分析值 ,比较 3种检查方法的阳性率。结果 :负荷后血中pH值降低 (t =6 42 6,P <0 0 0 1) ;CT、单纯静息显像和联合静息与负荷检查的阳性率分别为 2 3 5 %、2 9 4%和 70 6%。联合显像与CT检查阳性率差别有显著性意义 ( χ2 =6 12 5 ,P <0 0 1)。结论 :一日法口服乙酰唑胺负荷显像安全、省时、经济 ,可提高早期诊断缺血性脑血管疾病的阳性率。
Objective: To investigate the clinical value of one-day oral acetazolamide (ACZ) loaded cerebral perfusion imaging in the early diagnosis of ischemic cerebrovascular disease. Methods: Seventeen patients with ischemic cerebrovascular disease underwent static imaging and oral ACZ imaging in one day. Blood gas analysis was performed before and after loading. The positive rates of the three methods were compared. Results: After loading, the blood pH value decreased (t = 6 42 6, P 0 01). The positive rates of CT, simple resting imaging and combined resting and loading examination were 23.5% and 29 4% and 70 6%. There was a significant difference between the positive rates of CT and CT (χ2 = 6 12 5, P <0.01). Conclusion: One-day oral acetazolamide load imaging is safe, time-saving and economical, which can improve the positive rate of early diagnosis of ischemic cerebrovascular disease.