Efficient CAN catalyzed synthesis of 1H-indazolo[1,2-b] phthalazine-1,6,11-triones:An eco-friendly p

• 作 者: MAZAAHIR Kidwai RITIKA Chauhan ANWAR Jahan
• 机 构: Green Chemistry Research Laboratory,Department of Chemistry,University of Delhi,Delhi-110007,India,
• 出 处: Chinese Science Bulletin
• 发表日期: 2012年18期
• 关键词: ammonium aldehyde attractive inexpensive friendly render economically polyethyle

A convenient,economical and green approach to the synthesis of 1H-indazolo[1,2-b]phthalazine-1,6,11-trione derivatives has been achieved via a one-pot protocol using phthalhydrazide,a cyclic-β-diketone and an aldehyde in the presence of a ceric ammonium nitrate catalyst in polyethylene glycol.The simple work up,mild conditions,excellent yields,inexpensive and non-toxic catalyst and simple solvent recyclability render this protocol both attractive and economically viable.

A convenient, economical and green approach to the synthesis of 1H-indazolo [1,2-b] phthalazine-1,6,11-trione derivatives has been achieved via a one-pot protocol using phthalhydrazide, a cyclic-β-diketone and an aldehyde in the presence of a ceric ammonium nitrate catalyst in polyethylene glycol. simple work up, mild conditions, excellent yields, inexpensive and non-toxic catalyst and simple solvent recyclability render this protocol both attractive and economically viable.