论文部分内容阅读
Objective:To observe the anti-hypertensive effect of time acupuncture on primary hypertension so as to provide the therapeutic regimen for the treatment of primary hypertension.rnMethods:A total of 120 patients with primary hypertension were randomized into a western medication group and an acupuncture-medication group,60 cases in each one.In the western medication group,levoamlodipine maleate tablets were prescribed for oral administration.In the acupuncture-medication group,on the base of the treatment as the western medication group,time acupuncture was combined in the period of a day from 7:00 a.m.to 9:00 a.m.The duration of treatment was 4 weeks in the two groups.Before and after treatment,blood pressure,serum endothelin(ET)and nitrious oxide(NO)were measured successively and the clinical therapeutic effect was evaluated.rnResults:(1)Blood pressure:the systolic and diastolic pressure after treatment were all lower than that before treatment in the two groups,indicating statistical differences(all P ＜ 0.05).After treatment,the systolic and diastolic pressure in the acupuncture-medication group were lower than that of the western medication group,indicating significant differences(both P ＜ 0.05).(2)ET and NO:after treatment,ET in the acupuncture-medication group was lower than the western medication group and NO was higher than the western medication group,indicating statistical differences(both P ＜ 0.05).(3)Clinical thera-peutic effect:the total effective effect of anti-hypertension was 89％in the acupuncture-medication group,higher than 63％in the western medication group,indicating statistical difference(P ＜ 0.05).rnConclusion:The combined treatment of western medication and time acupuncture(7:00 am to 9:00 am)achieves better effect on primary hypertension as compared with simple western medication and its anti-hypertensive effect is probably related to the decrease of ET and the increase of NO.