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为了解乙型肝炎（乙肝）疫苗的免疫后效果，于1997年9～12月在上海、成都、兰州、肝春4个城市，采用整群随机抽样法抽取城区和郊区3～4岁儿童1271人调查，结果表明：1993～1994年新生儿乙肝疫苗接种丰城区为92.14％，明显高于郊区的76.97％。HBsAg阳性率降至2.28％，抗-HBS阳性率平均为71.28％．城区儿童未发现HBsAg阳性者，郊区儿童HBSAg阳性率为3.36％说明郊区是HBSAg阳性者的主要来源．此结果表明，我国乙肝疫苗免疫效果显著，但在郊区乙肝疫苗免疫工作有待加强。
In order to understand the post-immune effect of Hepatitis B (HBV) vaccine, a random sample of 1271 in urban and suburban areas aged 3 to 4 years was collected from September to December 1997 in four cities of Shanghai, Chengdu, Lanzhou and Hechunchun Survey, the results show that: 1993 to 1994 neonatal hepatitis B vaccination Fengcheng District was 92.14%, significantly higher than the suburbs of 76.97%. HBsAg positive rate dropped to 2.28%, anti-HBs positive rate was 71.28%. In urban areas, HBsAg positive children were not found, and the positive rate of HBSAg in suburban children was 3.36%, indicating that the suburbs are the main source of HBSAg positive people. The results show that the effect of hepatitis B vaccine in China is significant, but in the suburbs of hepatitis B vaccine need to be strengthened.