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目的:评价阿米替林对带状疱疹患者神经痛的临床效果。方法:选取2014年8月—2016年8月期间收治的带状疱疹神经痛患者82例作为研究对象,将其随机分为观察组41例和对照组41例;对照组患者给予卡马西平治疗,观察组患者在对照组患者治疗基础上给予阿米替林治疗,评价两组患者治疗后的总有效率。结果:观察组患者治疗2周、3周、4周后经视觉模拟量表(VAS)和睡眠治疗评分法(QS)的疼痛评分值均低于对照组(P<0.05);观察组患者治疗3周、4周后睡眠质量评分值均低于对照组(P<0.05),治疗的总有效率高于对照组(P<0.05)。结论:阿米替林用于治疗带状疱疹患者神经痛的临床疗效较好,能有效改善患者的临床症状。
Objective: To evaluate the clinical effect of amitriptyline on neuralgia in patients with herpes zoster. Methods: 82 patients with herpes zoster neuralgia who were treated in our hospital from August 2014 to August 2016 were selected as the research object, which were randomly divided into observation group (41 cases) and control group (41 cases). Patients in the control group were treated with carbamazepine The patients in the observation group were treated with amitriptyline on the basis of the treatment of the control group, and the total effective rate of the two groups was evaluated. Results: The pain score of the observation group was lower than that of the control group (P <0.05) after 2 weeks, 3 weeks and 4 weeks of treatment by VAS and QS; The scores of sleep quality at 3 weeks and 4 weeks were lower than that of the control group (P <0.05), and the total effective rate of treatment was higher than that of the control group (P <0.05). Conclusion: Amitriptyline for the treatment of neuralgia in patients with herpes zoster better clinical efficacy, can effectively improve the clinical symptoms of patients.