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目的探讨老年卧床感染患者甲状腺激素水平与病情严重程度及预后的关系。方法用放射免疫法测定48例老年卧床感染患者(卧床组)血浆三碘甲状腺原氨酸(T3)、甲状腺素(T4)及促甲状腺素(TSH)水平,并与45例非卧床老年感染患者(对照组)作比较,观察两组的差异性。结果与对照组比较,卧床患者T3、T4均明显降低,差异有统计学意义(P<0.01),TSH两组比较,差异无统计学意义(P>0.05)。卧床组中死亡12例,其T3、T4水平均明显低于该组中成活者,差异有统计学意义(P<0.01)。结论老年卧床患者中存在正常甲状腺功能病态综合征,并可作为预后不良的指标。
Objective To investigate the relationship between thyroid hormone levels and the severity and prognosis of elderly bedridden patients. Methods The levels of plasma triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH) were measured by radioimmunoassay in 48 elderly patients with bedridden infection (bedridden group) (Control group) for comparison, to observe the difference between the two groups. Results Compared with the control group, T3 and T4 in ambulatory patients were significantly lower (P <0.01). There was no significant difference in TSH between the two groups (P> 0.05). There were 12 deaths in the bedridden group, and the T3 and T4 levels in the bedridden group were significantly lower than those in the survivors. The difference was statistically significant (P <0.01). Conclusion The elderly patients with bedridden normal thyroid dysfunction syndrome, and can be used as an indicator of poor prognosis.