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目的观察疏血通注射液对系统性红斑狼疮继发肺动脉高压(SLE-PAH)的疗效。方法选取SLE-PAH患者60例,随机分成2组各30例,对照组予常规激素+环磷酰胺片治疗,疏血通组在常规治疗基础上加用疏血通注射液治疗。观察2组患者在治疗前后的症状、肺动脉压力和血D-二聚体的变化。结果与对照组比较,疏血通组患者的症状改善总有效率明显升高,肺动脉高压和血D-二聚体等均显著下降,2组比较均具有显著性差异(P均<0.05)。结论疏血通注射液治疗SLE-PAH效果显著,值得推广。
Objective To observe the effect of Shuxuetong injection on systemic lupus erythematosus secondary pulmonary hypertension (SLE-PAH). Methods Sixty patients with SLE-PAH were randomly divided into two groups of 30 patients. The control group was treated with conventional hormone plus cyclophosphamide. Shuxuetong group was treated with Shuxuetong injection on the basis of routine treatment. Two groups of patients before and after treatment of symptoms, pulmonary artery pressure and blood D-dimer changes. Results Compared with the control group, the total effective rate of symptom improvement and the pulmonary hypertension and D-dimer in Shuxuetong group were significantly decreased. There were significant differences between the two groups (all P <0.05). Conclusion Shuxuetong injection treatment of SLE-PAH significant effect, it is worth promoting.