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目的探讨治疗绝经后萎缩性阴道炎的最佳方案,提高临床治愈率,降低复发率。方法选择萎缩性阴道炎100例,采用随机对照分组,观察组尼尔雌醇+欧维婷+甲硝唑泡腾片治疗50例,对照组欧维婷+甲硝唑泡腾片治疗50例,停药7~10 d观察疗效,3个月后复查疗效,比较治疗效果。结果两组一疗程(7 d)有效率均为100%;3月后观察组无复发,对照组复发率30%,两组比较差异有统计学意义。结论雌激素联合抗生素阴道给药,可有效治疗萎缩性阴道炎,加用尼尔雌醇全身用药可降低复发率。
Objective To explore the best treatment for postmenopausal atrophic vaginitis, to improve the clinical cure rate and reduce the recurrence rate. Methods Atrophic vaginitis (n = 100) was enrolled in this study. Randomized control group (n = 50) was used in the observation group and 50 cases in the control group were treated with Ouwei Ting + metronidazole effervescent tablet ~ 10 d observation curative effect, 3 months after the curative effect, compare the curative effect. Results The effective rates were 100% in two groups after one course of treatment (7 days). No recurrence was observed in the observation group after 3 months, and the recurrence rate in the control group was 30%. There was significant difference between the two groups. Conclusions Estrogen combined with vaginal vaginal administration of antibiotics can effectively treat atrophic vaginitis, and systemic administration of nylestriol can reduce the recurrence rate.