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奴卡氏菌病为世界性分布的感染性疾病,可侵犯任何脏器,然播散性皮肤损害却不常见,其脓毒性关节炎更为罕见。作者报道1例糖尿病患者,因患颞动脉炎,在全身应用皮质类固醇激素治疗期间,出现了继发于肺部星形奴卡氏菌感染而播散的多形性皮损和脓毒性关节炎。通过对脓液、痰液及滑液的革兰氏染色和抗酸染色,确立了诊断,并为培养和组织病理所证实。该患者经2周的静脉注射TMP和SMZ,而后又改为口服治疗3个月,获得治愈。作者指出,奴卡氏菌为革兰氏阳性需氧菌,部分抗酸染色为阳性,其特点是能产生分枝状菌丝,不形成孢子。奴卡氏菌感染的发生率在合并其它疾病,
Nocardiosis is a worldwide infectious disease that can invade any organ, but disseminated skin lesions are uncommon and septic arthritis is more uncommon. The authors report that in one patient with diabetes, due to temporal arteritis, pleomorphic lesions and septic arthritis that developed secondary to pulmonary Aspergillus Nocardia infection were observed during systemic corticosteroid treatment . Through the Gram stain and acid-fast staining of pus, sputum and synovial fluid, a diagnosis was established and confirmed by culture and histopathology. The patient was given a 2-week intravenous infusion of TMP and SMZ, and then changed to oral treatment for 3 months to be cured. The authors point out that Nocardia is Gram-positive aerobic bacteria, some acid-fast staining is positive, which is characterized by the ability to produce branched mycelium, do not form spores. The incidence of Nocardiosis infection in the merger of other diseases,