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目的:探讨亚甲蓝宫颈注射宫颈癌前哨淋巴结(sentinellymphnodes,SLN)检测的临床价值。方法:13例宫颈癌患者亚甲蓝宫颈注射后行广泛子宫切除+盆腔淋巴结清扫术,蓝染淋巴结定为SLN,切除后行病检和(或)免疫组化染色,计算SLN准确性、敏感度、阴性预测值和假阴性率。结果:SLN准确性92.31%,敏感度75.00%,阴性预测值90.00%,假阴性率25.00%。结论:亚甲蓝宫颈注射宫颈癌SLN检测技术是可行的,能准确预测早期宫颈癌患者盆腔淋巴结病理状态。
Objective: To investigate the clinical value of cervical intracavernous cervical intraepithelial neoplasia sentinel lymph node (SLN) detection. Methods: Thirteen cases of cervical cancer were treated with extensive hysterectomy and pelvic lymphadenectomy after injection of methylene blue. The cervical lymph nodes were designated as SLN. After the resection, pathological examination and / or immunohistochemical staining were performed to calculate SLN accuracy and sensitivity Degree, negative predictive value and false negative rate. Results: The accuracy of SLN was 92.31%, the sensitivity was 75.00%, the negative predictive value was 90.00% and the false negative rate was 25.00%. Conclusion: SLN detection of cervical cancer cervical cancer is feasible, which can accurately predict the pathological status of pelvic lymph nodes in patients with early cervical cancer.