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目的:探讨运用家庭尿流检查（home-uroflowmetry，HUF）评估原发性夜间遗尿（primary nocturnal enuresis，PNE）的意义。方法:选取2019年12月至2021年3月在郑州大学第一附属医院泌尿外科门诊就诊的41例按照要求完成门诊尿流率检查（office-uroflowmetry，OUF）和48 h HUF的患儿。其中，男23例，年龄为（7. 3±2. 0）岁，范围为5~13岁，遗尿次数为2~7次/周；女18例，年龄为（7. 7±2. 3）岁，范围为5~14岁，遗尿次数为1~7次/周。分别记录患儿的排尿量（voided volume，VV）、最大尿流率（maximum urine flow rate，Qmax）、平均尿流率（average urine flow rate，Qave）、排尿时间（voiding time，VT）和尿流曲线进行统计分析。结果:OUF和48 h HUF分别记录到41次和568次（包括30次VV<50. 0 ml不能纳入统计分析）排尿。48 h HUF记录到的PNE患儿24 h排尿频率、夜间排尿频率、24 h VV和夜间尿量分别为（6. 9±1. 5）次、（1. 1±0. 5）次、（1 098. 1±163. 7) ml和（289. 6± 87. 2) ml。48 h HUF与OUF测得的VV为（163. 5±33. 0) ml比（209. 2±61. 7) ml，差异具有统计学意义（n P<0. 001）；Qmax为（19. 0±3. 2）ml/s比（20. 6±4. 5）ml /s，差异具有统计学意义（n P<0. 001）；Qave为（9. 3±1. 9）ml/s比（10. 3±2. 7）ml/s，差异具有统计学意义（n P=0. 001）；VT为（17. 9±3. 1) s比（20. 9±4. 6) s，差异具有统计学意义（n P<0. 001）。Altman-Bland分析显示VV、Qmax、Qave和VT分别仅有13/41、20/41、29/41和16/41的点位于临床可接受界限内，一致性差。对尿流曲线进行分析发现，OUF中Staccato尿流曲线发生率明显高于HUF （19. 5%比6. 3%）。n 结论:HUF的结果更加符合患儿的生理状态，更加真实可靠，在条件允许情况下优先选取HUF评估PNE患儿膀胱功能。“,”Objective:To explore the significance of home-uroflowmetry (HUF) in assessing primary nocturnal enuresis (PNE).Methods:From December 2019 to March 2021, 41 children visited our urology clinic and completed office-uroflowmetry (OUF) and 48 h HUF as required. Among them, 23 boys had an average age of (7. 3±2. 0) (5-13) years and the weekly number of enuresis ranged from 2 to 7 times; 18 girls had an average age of (7. 7±2. 3) (5-14) years and the weekly frequency of enuresis ranged from 1 to 7 times. Voided volume (VV) , maximal urine flow rate (Qmax) , average urine flow rate (Qave) , voiding time (VT) and urine flow curve were recorded for statistical analysis.Results:Forty-one and 568 voids (including 30 VV<50. 0 ml not included for statistical analysis) were recorded by OUF and 48 h HUF respectively. And 24 h urination frequency, nocturnal urination frequency, 24 h VV and nocturnal urine volume of PNE children recorded by 48 h HUF were (6. 9±1. 5) times, (1. 1± 0. 5) times, (1 098. 1±163. 7) ml and (289. 6±87. 2) ml respectively. VV measured by 48 h HUF and OUF was (163. 5±33. 0) vs. (209. 2±61. 7) ml and the difference was statistically significant (n P<0. 001) ; Qmax (19. 0±3. 2) vs. (20. 6±4. 5) ml/s and the difference was statistically significant (n P< 0. 001) ; Qave (9. 3±1. 9) vs. (10. 3±2. 7) ml/s and the difference was statistically significant (n P= 0. 001) ; VT (17. 9±3. 1) vs. (20. 9±4. 6) s and the difference was statistically significant (n P< 0. 001 ) . Altman-Bland analysis revealed that only 13/41, 20/41, 29/41 and 16/41 points for VV, Qmax, Qave and VT were all within clinically acceptable limits with a poor agreement. Analysis of urine flow curves revealed that the incidence of Staccato urine flow curve was significantly higher in OUF than in HUF (19.5% vs. 6. 3%) .n Conclusion:The results of HUF correspond more to the physiological status of children. More real and reliable, HUF is preferentially selected for assessing bladder function in PNE children.