Lynch syndrome and Lynch syndrome mimics: The growing complex landscape of hereditary colon cancer

• 作 者: John M Carethers Elena M Stoffel
• 机 构: DivisionofGastroenterologyDepartmentofInternalMedicineUniversityofMichigan,ComprohensiveCancerCenter
• 出 处: World Journal of Gastroenterology
• 发表日期: 2015年31期
• 关键词: HEREDITARY non-polyposis colorectal cancer LYNCH s Hereditary non-polyposis colo

Hereditary non-polyposis colorectal cancer(HNPCC) was previously synonymous with Lynch syndrome; however,identification of the role of germline mutations in the DNA mismatch repair(MMR) genes has made it possible to differentiate Lynch syndrome from other