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本文评价胺碘酮对常规治疗失败的房颤的价值。 38例症状性房颤,至少用过两种抗心律失常药无效,电复律后又复发。于30分钟内静滴胺碘酮5 mg/kg;继以口服每日600～800 mg,7～10日后改为每日200～400 mg。平均治疗16(3～35)个月。每1～3个月进行Holter心电图监测1次。胺碘酮治疗后,25例持久性房颤的19例(76%)恢复窦性心律,其中8例(32%)单用胺碘酮3日至3个月后转复,11例(44%)胺碘酮配合直流电转复成功;6例无效。长程治疗(16±9个月)的24例(维持量每日232
This article evaluates the value of amiodarone for routine treatment of failed atrial fibrillation. 38 cases of atrial fibrillation, at least two anti-arrhythmic drugs used ineffective, cardioversion and recurrence. Intravenous infusion of amiodarone 5 mg / kg within 30 minutes; followed by oral 600 ~ 800 mg daily, 7 to 10 days later changed to 200 ~ 400 mg daily. The average treatment of 16 (3 to 35) months. Every 1 to 3 months Holter ECG monitoring 1 time. Nineteen (76%) of 25 patients with persistent atrial fibrillation recovered sinus rhythm after amiodarone treatment, 8 (32%) with Amiodarone alone 3 to 3 months later, and 11 (44 %) Amiodarone with DC successfully restored; 6 ineffective. Long-term treatment (16 ± 9 months) in 24 patients (maintenance dose 232 per day