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本研究选择10μg/ml、20μg/ml、40μg/ml浓度的溴氰菊酯处理白纹伊蚊C6/36细胞,以MMC作为阳性对照物,观察溴氰菊酯处理24h后对C6/36细胞染色体畸变率和姐妹染色单体互换(SCE)频率的影响。结果显示,三个浓度的溴氰菊酯对C6/36细胞染色体畸变率均没有显著影响(P<0.05);溴氰菊酯浓度在40μg/ml时可诱导C6/36细胞SCE频率轻度增高(P>0.05),而溴氰菊酯浓度在10μg/ml、20μg/ml时,对C6/36细胞SCE频率没有诱导作用。表明溴氰菊酯对C6/36细胞的遗传学效应较弱
In this study, C. albicans C6 / 36 cells were treated with 10μg / ml, 20μg / ml and 40μg / ml deltamethrin. MMC was used as a positive control. The effect of deltamethrin on C6 / 36 cells Chromosome aberration rate and sister chromatid exchange (SCE) frequency. The results showed that all the three concentrations of deltamethrin had no significant effect on the chromosome aberration rate of C6 / 36 cells (P <0.05). When the concentration of deltamethrin was 40μg / ml, the SCE frequency of C6 / 36 cells was decreased (P> 0.05). When deltamethrin concentration was 10μg / ml and 20μg / ml, the SCE frequency of C6 / 36 cells was not induced. The delta cypermethrin showed weaker genetic effects on C6 / 36 cells