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目的了解杭州市男男性接触(men who have sex with men,MSM)人群和单阳家庭中人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染者早期抗病毒治疗可接受性的现况,探讨早期抗病毒治疗可接受性的影响因素。方法对于2012年7月前报告的符合纳入标准的调查对象进行统一问卷调查。结果共收集有效调查问卷235份,其中159人愿意接受早期抗病毒治疗,占67.66%,MSM感染者和HIV抗体单阳家庭感染者愿意接受早期治疗的比例分别是65.63%和76.74%,两者之间差异无统计学意义(χ2=1.99,P=0.16)。认为早期治疗会延缓发病和认为治疗越晚越易产生耐药性是早期治疗可接受性的促进因素,而认为早期治疗会让周围人怀疑自己有病和文化水平偏高是阻碍因素。结论杭州市MSM人群和HIV抗体单阳家庭中HIV阳性感染者愿意接受早期抗病毒治疗的比例较低,做好对早期抗病毒治疗的正确导向和积极宣传,提高对艾滋病早期治疗的认识,减少社会对感染者的歧视有利于早期抗病毒治疗的推广和预防艾滋病的传播。
Objective To understand the acceptability of early antiviral therapy in people with HIV infection in men who have sex with men (MSM) and single-positive families in Hangzhou, Influencing factors of acceptability of virus treatment. Methods The questionnaires that meet the inclusion criteria reported before July 2012 were collected. Results A total of 235 valid questionnaires were collected, of whom 159 were willing to receive early ART, accounting for 67.66%. The proportion of MSM-infected and HIV-single-positive families receiving early treatment was 65.63% and 76.74%, respectively The difference was not statistically significant (χ2 = 1.99, P = 0.16). It is considered that early treatment delays the onset of disease and believes that the later the treatment is, the more likely it is to develop drug resistance as a contributing factor to the acceptability of early treatment. However, it is considered an impediment to early treatment to make the surrounding people suspect that they are sick and have a high level of education. Conclusion The proportion of HIV-positive HIV-positive patients in Hangzhou-MSM population and HIV-positive single-yang families willing to receive early ART is low, so that they can correctly guide and actively promote early ART and improve awareness of early treatment of AIDS and reduce Discrimination against people living with HIV is conducive to the promotion of early anti-viral treatment and the prevention of the spread of AIDS.