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目的探讨米非司酮联合乳酸依沙吖啶溶液治疗中期妊娠引产的临床效果。方法选取医院2012年12月-2013年12月收治的要求终止妊娠的健康妇女105例,随机分为观察组53例和对照组52例,对照组直接按传统方法常规消毒后行羊膜腔内穿刺及注入乳酸依沙吖啶溶液;观察组给予米非司酮及注入乳酸依沙吖啶溶液,比较2组临床效果。结果观察组患者平均引产时间比对照组明显缩短,加快了引产进程,降低了患者阴道出血量及胎盘胎膜的残留率,产道损伤明显减少,不仅减少了患者的痛苦,且使引产成功率明显高于对照组,差异有统计学意义(P<0.05)。结论米非司酮配伍乳酸依沙吖啶溶液治疗中期妊娠引产成功率高达100%,两者联合弥补了双方的缺点,大大缩短了引产时间,有效减少了胎盘胎膜残留,降低了清宫率,安全性高,是目前安全、可靠的终止中期妊娠的方法,值得临床推广应用。
Objective To investigate the clinical efficacy of mifepristone combined with ethacridine lactate in induction of labor induction in the second trimester of pregnancy. Methods A total of 105 healthy women who required termination of pregnancy from December 2012 to December 2013 in our hospital were randomly divided into observation group (n = 53) and control group (n = 52). The control group was routinely disinfected with amniocentesis And injected with ethacridine lactate solution; the observation group was given mifepristone and injected with ethacridine lactate solution, the clinical effects of two groups were compared. Results In the observation group, the average induction of labor was significantly shorter than that of the control group, speeding up the induction of labor, reducing the amount of vaginal bleeding and residual placental membranes, and obviously reducing the birth canal injury. This not only reduced the patient’s pain but also markedly improved the successful induction of labor Higher than the control group, the difference was statistically significant (P <0.05). Conclusion Mifepristone with lactic acid ethacridine solution in the treatment of mid-term pregnancy induced labor success rate as high as 100%, the two combined to make up for the shortcomings of both sides, greatly reducing the induction of labor, effectively reducing the residual placental membranes, reducing the curettage rate, High safety is the safe and reliable method to terminate mid-term pregnancy and is worthy of clinical promotion and application.