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分析50例前列腺增生(BPH)、6例前列腺癌(PCA)和40名对照组(C)患者血清睾丸酮(T)、雌二醇(E2)、孕酮(P)、黄体生成素(LH)、和促卵泡素(FSH)的测定结果。发现BPH和PCA组血清T稍低于C组,但血清FSH明显高于C组(P<0.05)。BPH组按不同年龄分成3组显示血清P随年龄增加而增加(P<0.05),T/E2比值随年龄增长而降低。结果提示性激素代谢的平衡紊乱与BPH和PCA的发生有一定关系。
Serum levels of testosterone, estradiol, progesterone and luteinizing hormone (LH) in 50 patients with benign prostatic hyperplasia (BPH), 6 patients with prostate cancer (PCA) and 40 controls (C) , And follicle stimulating hormone (FSH) determination results. The serum T of BPH and PCA group was lower than that of C group, but serum FSH was significantly higher than that of C group (P <0.05). The BPH group was divided into three groups according to different ages and showed that the serum P increased with age (P <0.05), and the T / E2 ratio decreased with age. The results suggest that the imbalance of sex hormone metabolism and BPH and PCA have a certain relationship.