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Ｐ~１６基因在多种类型癌细胞系中有高频率的缺失和突变，我们应用ＳＡＢＣ免疫组织化学方法，初步分析了Ｐ~１６与胃癌发生、发展的关系。１材料和方法以近年来我院手术治疗并经病理证实的胃癌标本５４例，癌旁粘膜组织１６例，慢性萎缩性胃炎１３例，分为３组。均经１０％福
P16 has a high frequency of deletions and mutations in many types of cancer cell lines. We applied SABC immunohistochemistry to analyze the relationship between P16 and the occurrence and development of gastric cancer. 1Materials and Methods In recent years, 54 cases of gastric cancer specimens were surgically treated in our hospital and confirmed by pathology. There were 16 cases of para-tumoral mucosal tissue and 13 cases of chronic atrophic gastritis, which were divided into 3 groups. After 10% blessing