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听神经瘤(AN)与单侧耳聋间的微妙关系,是耳聋中的一个比较特殊的问题。本文结合1例保守治疗后观察12年AN患者的随访结果,就AN的分期、症状与体征、外淋巴液采样及其生化实验探讨其早期诊断价值。 1 AN的发病与就诊 AN患者占颅内肿瘤的8％～10％,占后颅窝肿瘤的79％～91％,堪称区域性“肿瘤冠军”。AN患者中,处于耳科阶段的占75％,处于神经科阶段的占25％。AN占单侧耳聋患者的5％～25％AN的早期首发症状为单侧耳鸣、耳聋与失衡感,其中部分就诊于中医、内科或神经科外,绝大多数首诊或回归于耳科。我们接诊的单侧耳聋患者中,AN患者占2％～8％。
The subtle relationship between acoustic neuroma (AN) and unilateral deafness is a rather special problem in deafness. In this paper, a case of follow-up of 12 patients with AN after conservative treatment was observed. The clinical value of early diagnosis of AN staging, symptoms and signs, perilymph sampling and biochemical experiments were explored. 1 AN incidence and treatment of AN patients accounted for 8% to 10% of intracranial tumors, posterior cranial fossa tumors accounted for 79% to 91%, called the regional “cancer champion.” Among AN patients, 75% are in otology and 25% are in neurology. AN accounts for 5% ~ 25% of patients with unilateral deafness. The first symptom of AN is unilateral tinnitus, deafness and imbalance. Some of them are treated in traditional Chinese medicine, internal medicine or neurology. Most of them are diagnosed first or returned to the otology. Among the patients with unilateral deafness who we received, AN patients accounted for 2% to 8%.