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目的探讨肾脏病患者真菌感染发病率、临床表现特点及预后等。方法前瞻性观察了我科近３年半收治的肾脏病患者中真菌感染的情况，并对真菌感染者予抗真菌治疗。结果１３４３例各类肾脏病患者中并发真菌感染者５０例（占３．７％），医院感染３９例，院外感染１１例，其中多部位感染者１６例。易感因素为老年患者，透析患者、难治性肾病综合征或病理类型难治者，长期应用激素和免疫抑制剂。结论肾脏病患者并发真菌感染并不少见，医院感染占多数，肺部真菌感染预后差，关键在于及时发现与治疗，更重要在于预防
Objective To investigate the incidence of fungal infection in nephrotic patients, clinical features and prognosis. Methods A prospective observation of fungal infections in nephrotic patients admitted to our hospital for nearly three and a half years and antifungal treatment of fungal infections were performed. Results Among 1343 cases of all kinds of nephrotic patients, 50 cases (3.7%) had fungal infection, 39 cases had nosocomial infection, 11 cases had nosocomial infection, and 16 cases had multi-part infection. Susceptibility factors for elderly patients, dialysis patients, refractory nephrotic syndrome or pathological type refractory, long-term use of hormones and immunosuppressive agents. Conclusions It is not uncommon for patients with nephrotic syndrome complicated by fungal infection, the majority of nosocomial infections, and the poor prognosis of pulmonary fungal infections, the key lies in timely detection and treatment, and more importantly, prevention