Isolation of toxic compounds from wild Phaeocystis globosa

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:mumuww
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Two new compounds, namely taenialactam C and globorin A(1 and 2), as well as six known compounds,cornoside(3), 2-phenylethyl-b-D-glucoside(4), 3-isopropyl-5-acetoxycyclohexene-2-one-1(5), 4-methyl-phenol(6), 5-[(2S)-2-aminobutyl]-2-methyl-phenol(7), and 1-(4-methylphenyl)-1-propanone(8) were isolated from wild Phaeocystis globosa. The structures of the new compounds were established by detailed spectroscopic analysis and by comparison with spectral data of related known compounds.The structures of the known compounds were identified by comparing their spectroscopic data with those reported in the literature. This paper also reports toxicity properties of the eight compounds against the brine shrimp Artemia salina and juvenile Epinephelus akaara fish. Some of these compounds showed significant lethality on the brine shrimp A. salina and the juvenile E. akaara fish. Two new compounds, namely taenialactam C and globorin A (1 and 2), as well as six known compounds, cornoside (3), 2-phenylethyl-bD-glucoside (4), 3-isopropyl-5- acetoxycyclohexene-2-one (7), and 1- (4-methylphenyl) -1-propanone (8) ) were isolated from wild Phaeocystis globosa. The structures of the new compounds were established by detailed spectroscopic analysis and by comparison with spectral data of related known compounds. structures of the known compounds were identified by comparing their spectroscopic data with those reported in the literature . This paper also reports toxicity properties of the eight compounds against the brine shrimp Artemia salina and juvenile Epinephelus akaara fish. Some of the compounds showed significant lethality on the brine shrimp A. salina and the juvenile E. akaara fish.
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