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决定心脏工作效能的诸因素,包括基本决定因素(心肌收缩性、前负荷、后负荷、心室舒张心期顺应性)和重要附加因素(心肌的弛张性、室收缩的协调性、心率/节律/传导、心肌代谢状态和心脏结构的完整性及心肌损伤程度),都可在不同程度上参与充血性心力衰竭(CHF)的发生。CHF可起因于:(1)原发性心肌收缩力减损(心肌衰竭);(2)心窒负荷过重(前、后负荷过重及组织需要增加);(3)心室舒张期充盈受限制(负荷不足)及(4)心室舒张期顺应性降低。
The factors that determine the performance of a heart work include basic determinants (myocardial contractility, preload, postload, ventricular diastolic compliance) and important additional factors (myocardial relaxation, coordination of ventricular contraction, heart rate / rhythm / Conduction, myocardial metabolic status and cardiac structural integrity and myocardial injury), may be involved in varying degrees, the occurrence of congestive heart failure (CHF). CHF can result from: (1) impairment of primary myocardial contractility (myocardial failure); (2) overloading of cardiac arrest (before and after overloading and increased tissue requirements); (3) restriction of ventricular diastolic filling (Under-load) and (4) reduced ventricular diastolic compliance.