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探讨口咽环黏膜相关淋巴组织型淋巴瘤的诊断标准、鉴别诊断及发病机制。采用活检或手术标本做石蜡切片、HE染色及免疫组化ABC法检测。 6例口咽环黏膜相关淋巴组织型淋巴瘤均为B细胞低度恶性。 1例为CCL型 ,1例为淋巴浆细胞型 ,4例为浆细胞型。免疫表型IgG、IgM为主 ,缺乏IgD。局部生长缓慢 ,较少转移 ,临床预后较好。因此手术为首选疗法。对口咽环黏膜慢性炎 ,应予以有效抗菌治疗 ,并注意与黏膜相关淋巴组织型淋巴瘤鉴别。
To investigate the diagnostic criteria, differential diagnosis and pathogenesis of oropharyngeal mucosa-associated lymphoid tissue lymphoma. Using biopsy or surgical specimens paraffin sections, HE staining and immunohistochemical ABC method. 6 cases of oropharyngeal mucosa-associated lymphoid tissue lymphoma were low grade B cell malignant. 1 case was CCL type, 1 case was lymphocyte plasma cell type, and 4 cases was plasma cell type. Immunophenotype IgG, IgM-based, the lack of IgD. Local growth is slow, less metastasis, the clinical prognosis is better. Therefore, surgery is the preferred therapy. Chronic inflammation of the oropharyngeal mucosa, should be effective antibacterial therapy, and pay attention to mucosal lymphoid tissue-associated lymphoma identification.