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52例FBG≥11.1mmol/L,2hPG≥14mmol/L住院的初诊2型糖尿病患者,给予胰岛素泵强化治疗一周,不合用其他口服降糖药,观察达到目标血糖(FBG<7mmol/L,2hBG<10mmol/L)的天数及胰岛素泵的基础量和餐前大剂量。结果达到目标血糖的平均天数为5.1±1.7(天),胰岛素的日基础量为0.28±0.05(u/kg),日餐前大剂量为0.36±0.13(u/kg)。发生低血糖症0.03±0.17(次/人),低血糖反应0.96±0.22(次/人),生化低血糖0.06±0.28(次/人)。结论对伴有明显高血糖的2型初诊糖尿病患者,短期胰岛素泵的强化治疗具有快速平稳降血糖作用,从而改善胰岛β细胞功能。
52 patients with FBG ≥11.1mmol / L, 2hPG≥14mmol / L were hospitalized newly diagnosed type 2 diabetic patients, given insulin pump intensive treatment for one week, do not use other oral hypoglycemic agents to observe the target blood glucose (FBG <7mmol / L, 2hBG < 10mmol / L) days and the basic amount of insulin pump and pre-meal high-dose. Results The mean number of days to achieve the target blood glucose was 5.1 ± 1.7 days, the basal daily dose of insulin was 0.28 ± 0.05 (u / kg), and the pre-Japanese bolus dose was 0.36 ± 0.13 (u / kg). Hypoglycemia 0.03 ± 0.17 (times / person), hypoglycemia response 0.96 ± 0.22 (times / person), biochemical hypoglycemia 0.06 ± 0.28 (times / person). Conclusions Intensive treatment with short-term insulin pump has a rapid and stable hypoglycemic effect on type 2 newly diagnosed diabetic patients with significant hyperglycemia, thereby improving pancreatic β-cell function.