论文部分内容阅读
目的分析血清腹水白蛋白梯度(SAAG)在鉴别门脉高压性与非门脉高压性腹水中的临床价值。方法选取2012年7月至2014年4月100例腹水患者为研究对象,其中门脉高压性腹水60例为观察组,非门脉高压性腹水40例为对照组,通过全自动生化检测仪测定并比较两组患者血清腹水白蛋白、腹水总蛋白(AFTP)水平。结果观察组SAAG水平为(17.85±4.67)g/L,对照组为(11.04±6.75)g/L,两组比较差异有统计学意义(P<0.01);观察组SAAG≥11 g/L者57例,对照组2例,差异有统计学意义(P<0.01)。SAAG≥11 g/L对门脉高压性腹水诊断敏感度、特异性均为95.00%,与AFTP<25 g/L的55.00%、80.00%比较差异有统计学意义(P<0.05)。另外,SAAG≥11 g/L者食管静脉曲张发生率明显高于SAAG<11 g/L者(P<0.01)。结论血清腹水白蛋白梯度≥11 g/L可作为门脉高压性与非门脉高压性腹水鉴别的重要指标,且对食管静脉曲张有一定的预测价值。
Objective To analyze the clinical value of serum ascites albumin gradient (SAAG) in distinguishing portal hypertension from non-portal hypertensive ascites. Methods From July 2012 to April 2014, 100 cases of ascites were selected as the study subjects, of which 60 cases of portal hypertension ascites and 40 cases of non-portal hypertensive ascites as control group were determined by automatic biochemical analyzer Serum ascites albumin and ascites total protein (AFTP) levels were compared between the two groups. Results The level of SAAG in the observation group was (17.85 ± 4.67) g / L and in the control group was (11.04 ± 6.75) g / L, the difference was statistically significant (P <0.01) 57 cases, control group 2 cases, the difference was statistically significant (P <0.01). The sensitivity and specificity of SAAG≥11 g / L for the diagnosis of portal hypertension ascites were 95.00%, which were significantly different from those of 55.00% and 80.00% for AFTP <25 g / L (P <0.05). In addition, the incidence of esophageal varices with SAAG> 11 g / L was significantly higher than that with SAAG <11 g / L (P <0.01). Conclusion Serum ascites albumin gradient ≥ 11 g / L can be used as portal hypertension and non-portal hypertensive ascites identification of important indicators, and esophageal varices have a certain predictive value.