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1例29岁男性因车祸致颅脑损伤住院。住院期间为改善微循环给予复方丹参注射液20 ml加入5%葡萄糖注射液250 ml,1次/d静脉滴注。治疗第6天出现皮肤紫癜,继之出现腹痛、双下肢关节疼痛和血尿。实验室检查:尿潜血(++),尿蛋白(++);血小板243×109/L;血浆凝血酶原时间13 s,活化部分凝血活酶时间36 s。停用复方丹参注射液,给予对症支持治疗,皮肤瘙痒、腹痛及关节痛症状逐渐缓解,停药1周后皮疹消退,尿常规各项检查均恢复正常。
A 29-year-old man hospitalized for craniocerebral injury due to a car accident. In order to improve microcirculation during hospitalization to give compound Danshen injection 20 ml 5% glucose injection 250 ml, 1 / d intravenous infusion. Skin purpura appeared on the 6th day of treatment, followed by abdominal pain, joint pain and hematuria of both lower extremities. Laboratory tests: urinary occult blood (++), urinary protein (++); platelets 243 × 109 / L; plasma prothrombin time 13 s, activated partial thromboplastin time 36 s. Compound Danshen injection was discontinued, symptomatic supportive treatment was given, skin itching, abdominal pain and symptoms of joint pain were gradually relieved. After one week of withdrawal, the rash subsided and the urine routine returned to normal.