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目的探索肉毒杆菌毒素Ａ（ＢＴＸ －Ａ）肌肉注射配合综合康复矫治小儿脑性瘫痪（脑瘫）功能畸形的疗效。方法４８例脑瘫患儿随机分为两组，观察组２４例，运用ＢＴＸ －Ａ和综合康复治疗；对照组２４例，采用综合康复疗法。结果两组总有效率分别为１００％和７５％，观察组明显优于对照组（χ２＝４．７６；Ｐ＜０．０５）。结论ＢＴＸ －Ａ肌肉注射与综合康复疗法结合治疗小儿脑瘫能明显提高疗效。
Objective To explore the efficacy of intramuscular injection of botulinum toxin A (BTX-A) combined with comprehensive rehabilitation on functional deformities in children with cerebral palsy (cerebral palsy). Methods 48 cases of cerebral palsy children were randomly divided into two groups, the observation group of 24 cases, the use of BTX-A and comprehensive rehabilitation; control group of 24 patients, the use of comprehensive rehabilitation therapy. Results The total effective rate was 100% and 75% respectively in the two groups. The observation group was significantly better than the control group (χ2 = 4.76; P <0.05). Conclusion BTX-A intramuscular injection combined with comprehensive rehabilitation therapy for children with cerebral palsy can significantly improve the efficacy.