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目的探讨鞍区肿瘤术后单纯尿崩症的发生特点及处理原则。方法回顾性分析53例鞍区肿瘤病人术后并发单纯性尿崩的临床特点及治疗原则。结果术后尿崩呈暂时型48例(90.5%),三相型3例(5.7%),持续型2例(3.8%)。因严重尿崩死亡1例(1.9%)。余病人随访6个月,尿崩症痊愈48例(90.5%),永久性尿崩4例(7.6%)。结论尿崩症的发生类型与手术方式、肿瘤大小等相关。选择适当的手术方式,术后严密监测尿量和血电解质,积极纠正水、电解质紊乱,是处理尿崩症的关键,其可以有效降低手术病死率。
Objective To investigate the characteristics and treatment principles of simple diabetes insipidus after sellar tumor surgery. Methods Retrospective analysis of 53 cases of sellar tumor patients with simple diabetes insipidus clinical features and treatment principles. Results Postoperative uremic collapse was transient in 48 cases (90.5%), three-phase in 3 cases (5.7%) and persistent type in 2 cases (3.8%). One patient died of severe diabetes insult (1.9%). Six patients were followed up for more than 6 months. 48 cases (90.5%) had diabetes insipidus and 4 cases (7.6%) had permanent diabetes insipidus. Conclusion The occurrence of diabetes insipidus is related to the operation method, tumor size and so on. Select the appropriate surgical methods, close monitoring of urine output and blood electrolytes, and actively correct water and electrolyte disorders, is the key to the treatment of diabetes insipidus, which can effectively reduce the operative mortality.